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Social and Ethical Implications of Polygenic Risk (SEIPR)


The Social and Ethical Implications of Polygenic Risk (SEIPR, “see-per”) WG will identify, investigate, and respond to ethical, social, and related considerations that may arise over the course of the PRIMED Consortium. The development and use of polygenic risk scores (PRS) constitutes an exciting new scientific area but is fraught with numerous challenges related to equity application across diverse ancestral groups, and suitability for clinical use, among others. The WG will identify specific challenges to address based on member input and then provide structured discussions around each issue, outlining specific issues of concern. Synopses of each challenge addressed will be provided to the PRIMED Steering Committee, along with materials for the wider research community when warranted.