The NIH-funded Polygenic Risk Methods in Diverse Populations (PRIMED) Consortium is developing and evaluating methods to improve the use of polygenic risk scores (PRS) to predict disease and health outcomes in diverse ancestry populations.
Learn more about PRIMED Consortium research and ways to get involved.
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The NIH will fund grants totaling $38 million over five years to develop methods that will improve the way that polygenic risk scores can be used to predict disease in diverse communities.
Jin Jin, et al. ME-Bayes SL: Enhanced Bayesian Polygenic Risk Prediction Leveraging Information across Multiple Ancestry Groups bioRxiv.
Ding, Yi, et al. Polygenic scoring accuracy varies across the genetic ancestry continuum bioRxiv.