The NIH-funded Polygenic Risk Methods in Diverse Populations (PRIMED) Consortium is developing and evaluating methods to improve the use of polygenic risk scores (PRS) to predict disease and health outcomes in diverse ancestry populations. 

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Image of multicultural people, with genetic sequencing over the globe. Credit: National Human Genome Research Institute
NIH awards $38 million to improve utility of polygenic risk scores in diverse populations

The NIH will fund grants totaling $38 million over five years to develop methods that will improve the way that polygenic risk scores can be used to predict disease in diverse communities.


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Colorful image of multiple open journals. Image by kconcha from Pixabay.
Recent publications
Chou, Alisha, et al. Association of prostate-specific antigen levels with prostate cancer risk in a multiethnic population: Stability over time and comparison with polygenic risk score. Cancer Epidemiology, Biomarkers & Prevention.
Jee, Yon Ho, et al. Polygenic Risk Scores for Prediction of Breast Cancer in Korean women. International Journal of Epidemiology.

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