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The NIH-funded Polygenic Risk Methods in Diverse Populations (PRIMED) Consortium is developing and evaluating methods to improve the use of polygenic risk scores (PRS) to predict disease and health outcomes in diverse ancestry populations. 

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Learn more about PRIMED Consortium research and ways to get involved.

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illustration of Earth with a DNA strand stretching across it and symbols of people in all different colors
PRIMED featured in NHGRI Director's newsletter

The PRIMED Perspective is featured in the January 2025 "The Genomics Landscape," a monthly newsletter from NHGRI Director Eric Green, M.D., Ph.D., featuring activities and accomplishments from the institute and the field of genomics. The Perspective outlines goals, approaches, and ongoing activities, including new PRS methods and models.

Colorful image of multiple open journals. Image by kconcha from Pixabay.
Recent publications
Ebuka Onyenobi, et al. Development and Validation of Polygenic Risk Scores for Blood Pressure Traits in Continental African Populations .
Dias, Julie-Alexia, et al. Evaluating Multi-Ancestry Genome-Wide Association Methods: Statistical Power, Population Structure, and Practical Implications medRxiv.

See more