The NIH-funded Polygenic Risk Methods in Diverse Populations (PRIMED) Consortium is developing and evaluating methods to improve the use of polygenic risk scores (PRS) to predict disease and health outcomes in diverse ancestry populations. 

For Researchers

Learn more about PRIMED Consortium research and ways to get involved.

For Consortium Members

Visit your customized dashboard to view consortium information.

illustration of Earth with a DNA strand stretching across it and symbols of people in all different colors
PRIMED featured in NHGRI Director's newsletter

The PRIMED Perspective is featured in the January 2025 "The Genomics Landscape," a monthly newsletter from NHGRI Director Eric Green, M.D., Ph.D., featuring activities and accomplishments from the institute and the field of genomics. The Perspective outlines goals, approaches, and ongoing activities, including new PRS methods and models.

Colorful image of multiple open journals. Image by kconcha from Pixabay.
Recent publications
Sun, Quan, et al. Polygenic Scores of Cardiometabolic Risk Factors in American Indian Adults JAMA Network Open.
Kharitonova, Elena, et al. EndoPRS: Incorporating endophenotype information to improve polygenic risk scores for clinical endpoints—A study in asthma American Journal of Human Geneics.

See more