The NIH-funded Polygenic Risk Methods in Diverse Populations (PRIMED) Consortium is developing and evaluating methods to improve the use of polygenic risk scores (PRS) to predict disease and health outcomes in diverse ancestry populations. 

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Image of multicultural people, with genetic sequencing over the globe. Credit: National Human Genome Research Institute
NIH awards $38 million to improve utility of polygenic risk scores in diverse populations

The NIH will fund grants totaling $38 million over five years to develop methods that will improve the way that polygenic risk scores can be used to predict disease in diverse communities.


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Colorful image of multiple open journals. Image by kconcha from Pixabay.
Recent publications
Jin Jin, et al. ME-Bayes SL: Enhanced Bayesian Polygenic Risk Prediction Leveraging Information across Multiple Ancestry Groups bioRxiv.
Ding, Yi, et al. Polygenic scoring accuracy varies across the genetic ancestry continuum bioRxiv.

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