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Testing the generalizability of ancestry-specific polygenic risk scores to predict prostate cancer in sub-Saharan Africa. Genome Biology
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Polygenic risk scores for prediction of breast cancer risk in women of African ancestry: a cross-ancestry approach. Human Molecular Genetics
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Improving the computation efficiency of polygenic risk score modeling: faster in Julia. Life Science Alliance
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Genome-wide polygenic score to predict chronic kidney disease across ancestries. Nature Medicine
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Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations. Genome Medicine
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TOP-LD: A tool to explore linkage disequilibrium with TOPMed whole-genome sequence data. The American Journal of Human Genetics
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Polygenic risk score for peripheral artery disease: A tool to refine risk stratification. Vascular Medicine
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Polygenic risk scores for CARDINAL study. Nature Genetics
May 2022
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Improving polygenic prediction in ancestrally diverse populations. Nature Genetics
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Development of a clinical polygenic risk score assay and reporting workflow. Nature Medicine
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Risk Stratification for Early-Onset Colorectal Cancer Using a Combination of Genetic and Environmental Risk Scores: An International Multi-Center Study. J Nat Cancer Institute
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Association of the Interaction Between Familial Hypercholesterolemia Variants and Adherence to a Healthy Lifestyle With Risk of Coronary Artery Disease JAMA Network Open
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Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts Diabetes Care
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Super interactive promoters provide insight into cell type-specific regulatory networks in blood lineage cell types. PLoS Genetics
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eSCAN: scan regulatory regions for aggregate association testing using whole-genome sequencing data Briefings in Bioinformatics
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Fast estimation of genetic correlation for biobank-scale data. The American Journal of Human Genetics
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Large uncertainty in individual polygenic risk score estimation impacts PRS-based risk stratification. Nature Genetics
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Predicting diabetes risk in diverse populations: what next? The Lancet. Diabetes & Endocrinology
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Selection of 51 predictors from 13,782 candidate multimodal features using machine learning improves coronary artery disease prediction Patterns
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