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Testing the generalizability of ancestry-specific polygenic risk scores to predict prostate cancer in sub-Saharan Africa. Genome Biology
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Polygenic risk scores for prediction of breast cancer risk in women of African ancestry: a cross-ancestry approach. Human Molecular Genetics
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Use of polygenic risk scores for coronary heart disease in ancestrally diverse populations. Current Cardiology Reports
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Large-scale genome-wide association study of coronary artery disease in genetically diverse populations. Nature Medicine
Aug 2022
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Type 1 diabetes in diverse ancestries and the use of genetic risk scores. The Lancet. Diabetes & Endocrinology
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Transcriptome-wide association study in UK Biobank Europeans identifies associations with blood cell traits. Human Molecular Genetics
Jul 2022
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Improving the computation efficiency of polygenic risk score modeling: faster in Julia. Life Science Alliance
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Validation of a multi-ancestry polygenic risk score and age-specific risks of prostate cancer: A meta-analysis within diverse populations. ELife
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Genome-wide polygenic score to predict chronic kidney disease across ancestries. Nature Medicine
Jul 2022
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Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations. Genome Medicine
Jun 2022
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Huang, Le
TOP-LD: A tool to explore linkage disequilibrium with TOPMed whole-genome sequence data. The American Journal of Human Genetics
Jun 2022
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Polygenic risk score for peripheral artery disease: A tool to refine risk stratification. Vascular Medicine
Jun 2022
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Polygenic risk scores for CARDINAL study. Nature Genetics
May 2022
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Clinical utility of polygenic risk scores for coronary artery disease. Nature Reviews. Cardiology
May 2022
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Hao, Limin
Development of a clinical polygenic risk score assay and reporting workflow. Nature Medicine
May 2022
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Ruan, Yunfeng
Improving polygenic prediction in ancestrally diverse populations. Nature Genetics
May 2022
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Risk Stratification for Early-Onset Colorectal Cancer Using a Combination of Genetic and Environmental Risk Scores: An International Multi-Center Study. J Nat Cancer Institute
Apr 2022
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Fahed, Akl
Association of the Interaction Between Familial Hypercholesterolemia Variants and Adherence to a Healthy Lifestyle With Risk of Coronary Artery Disease JAMA Network Open
Mar 2022
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DiCorpo, Daniel
Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts Diabetes Care
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Recessive genome-wide meta-analysis illuminates genetic architecture of type 2 diabetes. Diabetes
Mar 2022
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Wen, Jia
Super interactive promoters provide insight into cell type-specific regulatory networks in blood lineage cell types. PLoS Genetics
Jan 2022
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Yang, Yingxi
eSCAN: scan regulatory regions for aggregate association testing using whole-genome sequencing data Briefings in Bioinformatics
Jan 2022
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Fast estimation of genetic correlation for biobank-scale data. The American Journal of Human Genetics
Jan 2022
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Ding, Yi
Large uncertainty in individual polygenic risk score estimation impacts PRS-based risk stratification. Nature Genetics
Jan 2022
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Predicting diabetes risk in diverse populations: what next? The Lancet. Diabetes & Endocrinology
Dec 2021
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Agrawal, Saaket
Selection of 51 predictors from 13,782 candidate multimodal features using machine learning improves coronary artery disease prediction Patterns
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