Currently, this website is not being updated or actively managed. Messages and webform submissions sent to the PRIMED Coordinating Center are also not being monitored or responded to at this time. This message will be removed when normal operations have resumed.
Diabetes Polygenic RIsk Scores in Multiple ancestries (D-PRISM) is led by Josep Mercader (contact PI) and Alisa Manning (MPI) from the Broad and Maggie Ng (MPI) from VUMC, along with 32 co-investigators across 5 countries. D-PRISM work will focus on improving polygenic risk score prediction of diabetes and progression across the lifespan in diverse ancestries using the PRS-CS method and its extensions. Their study includes more than 1.5M individuals with type 1 and type 2 diabetes, gestational diabetes and/or related complications from diverse ancestries. Results from this study will demonstrate how genomic data can inform more efficient and targeted preventive strategies within healthcare systems and across ethnically diverse populations.