The NIH-funded Polygenic Risk Methods in Diverse Populations (PRIMED) Consortium is developing and evaluating methods to improve the use of polygenic risk scores (PRS) to predict disease and health outcomes in diverse ancestry populations. 

For Researchers

Learn more about PRIMED Consortium research and ways to get involved.

For Consortium Members

Visit your customized dashboard to view consortium information.

PRIMED Consortium goals, working groups, products, and structure
Publication of PRIMED Perspective in AJHG

The PRIMED Perspective manuscript has been published, viewable on the AJHG website and ScienceDirect. In brief, this Consortium marker paper describes the PRIMED Consortium and organization of its activities, and highlights methodological innovations and early products, with the goal of facilitating additional initiatives that aim to reduce inequity in genomic medicine.

Kullo, I. J., Conomos, M. P., Nelson, S. C., Adebamowo, S. N., Choudhury, A., Conti, D., Fullerton, S. M., Gogarten, S. M., Heavner, B., Hornsby, W. E., Kenny, E. E., Khan, A., Khera, A. v., Li, Y., Martin, I., Mercader, J. M., Ng, M., Raffield, L. M., Reiner, A., … Zhong, M. (2024). The PRIMED Consortium: Reducing disparities in polygenic risk assessment. The American Journal of Human Genetics. https://doi.org/10.1016/j.ajhg.2024.10.010


Read more
Colorful image of multiple open journals. Image by kconcha from Pixabay.
Recent publications
Ruan, Yunfeng, et al. Leveraging multiple fine-tuning datasets and genetic ancestry continuum information to harmonize PRS for admixed populations medRxiv.
Johanna L Smith, et al. Comparative Performance of Polygenic Risk Scores for Atherosclerotic Cardiovascular Disease Subtypes in the All of Us Research Program medRxiv.

See more